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Department of Chemistry Liquid Phase Ion Mobility Spectrometry

Liquid IMS works on the same principle as gas phase IMS, the method of choice for the rapid detection of drugs and explosives. Because ions diffuse three orders of magnitude slower in liquids than in gases, real-time ion detection can take place in a miniaturized liquid phase IMS.

To complement this technique, our group has developed electrodispersion ionization(EDI) which is a novel ionization source for the liquid phase. Experimental data showed that EDI delivered inorganic and organic ions from aqueous solution into a non-ionic buffer liquid.

Ion current response
Total ion current response for 10 mM Basic Fuchsin in (a) air by ESI, (b) hexane by EDI and (c) benzene by EDI. ESI/EDI voltage was applied at ~15s and terminated at ~115 s
Corresponding photos of ionizing 10 mM Basic Fuchsin (a) by ESI in air, (b) by EDI in hexane and (c) by EDI in benzene
Corresponding photos of ionizing 10 mM Basic Fuchsin (a) by ESI in air, (b) by EDI in hexane and (c) by EDI in benzene